Creative Bios

  It's acknowledged that researchers rarely can perform direct experiments on human subjects. Therefore, model organisms become attractive examples to be studied when other species, especially humans, are not practical. Furthermore, a wealth of favorable characteristics also make model organism antibodies  become a hot spot.   Features of a Good Model Organism   Since model organisms are vital tools for global scientists to study and reveal universal biological phenomena and laws, a preferred model organism should universally be:   l  Conducive to answering concerned research questions, and with physiological characteristics representing a large biological group. l  Characterized with short generations, many offspring, easy to breed in the laboratory, and clear genetic background. l  Easy to perform experimental operations, especially genetic manipulations and phenotypic analysis.   To sum up, model organisms are typically chosen in terms of ...

  Human monoclonal antibody therapies, which embrace over 570 agents in the clinical field, have become one of the fastest-growing cancer treatment s . Now, a novel therapy based on bispecific antibodies may be a further refinement in oncology treatment that overcomes the limitations of current monoclonal antibody therapies.   What are Bispecific Antibodies?   Bispecific a ntibodies (BsAbs)  are engineered proteins that can simultaneously recognize and bind two separate and unique targets (antigens or different epitopes of the same antigen). Given the fact of dual functionalities, BsAbs are different from normal monoclonal antibodies.   Therapeutics and drugs based on bispecific antibodies are expected to be the next big advance in oncology, hematology in particular. Different from cytotoxic chemotherapy or targeted agents, the distinct mechanism of action of bispecific antibody drugs may enable patients to fight against cancers with  the immune system. ...