Biliary atresia (BA) is a congenital condition that a blockage happ ens in the tubes responsible for carry ing bile from the liver to the gallbladder. It results from abnormal development of the bile ducts inside or outside the liver and results in progressive fibrous obliteration with different degrees of inflammation in the hepatobiliary system. According to incomplete statistics, about 1 out of 10,000–20,000 live births would be identified with b iliary atresia , but actually, the situation could be worse given the late diagnoses. Up to now, the causes for this condition remain unclear and seem to be heterogeneous, but it undoubtedly would lead to an inestimable mental and financial burden for patients and their families, as well as the healthcare system. To better understand and identify the etiology of b iliary atresia , researchers are dedicated to finding the best animal model organism to ver...