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The Tumor Therapeutic Mechanism of Bispecific Antibodies

  The incidence and   c ase fatality rate of cancer is increasing with the deterioration of the global environment and the changes in people's living habits, which urges the development of anti-tumor drugs and related studies. Bispecific antibodies  (BsAbs) are one of the novel concepts that are regarded as the second-generation antibodies for tumor therapies with broad prospects.   Bispecific antibodies are featured  with a structure of binding to two different epitopes on the same or different antigens, which make them more efficient in the process of killing tumor cells. BsAbs can facilitate the recruitment and activation of immune cells and the blocking of tumor signaling pathways, as well as bind to Fc receptors and drugs.   T  cells present in the blood circulation of the whole body are one of the most important  and powerful immune cells to attack tumor cells. However, it's difficult for T cells to focus on a specific cancerous part of the ...