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Showing posts from October, 2022

Bacteriophages May Be Able to "Watch and Listen in" on Their Hosts

  A recent study published in Frontiers in Microbiology attracts researchers' attention because it reveals that some viruses might have the ability to monitor their surroundings and take action accordingly. T o be specific, viruses can sense the environment around themselves and their host and then decide whether or when to suspend their activities, spread infection, attack or kill the host cells, multiply, and burst out inside their hosts at any given time. T hi s finding is significant to uncover unknown interactions between viruses and their hosts and may have implications for the development of a new generation of antiviral drugs.   Bacteriophages , or simply phages, are viruses that infect and harm bacteria. In this study, researchers look into a phage that can only infect the host when the bacterial cells have special appendages—pili and flagella that can help the bacteria move and mate. Specifically, this flagellotropic phage infects Caulobacter bacteria cells, which ha...

Combination of Machine Learning Analytics and Proteomics for Better Diagnostics

  It's  highly recognized that digitized healthcare technologies present numerous possibilities and opportunities for reducing human errors, improving clinical outcomes, tracking data over time, etc. Due to  the ability to analyze vast amounts of data quickly and in detail, artificial intelligence (AI) methods, from machine learning to deep learning, are taking on more and more crucial functions in numerous healthcare domains, especially in identifying the diagnosis of different types of diseases.   AI-Based Biomarker Detection   T hriving digitized healthcare technologies enable  researchers and technicians from University College Dublin to combine proteomics, the large-scale study of proteins, with data science and machine learning analytics, to deliver highly specific and  personalized diagnostic information for various diseases. Their strategies are based on the concept that personalized medicine is the general  trend of future healthcare whic...

Phage Therapy: Promising Alternative to Control Multidrug-Resistant Pathogens

  Overuse  of antibiotics has heavily contributed to the prevalence of multidrug-resistant (MDR) and antimicrobial resistant (AMR) pathogens, the  result of which, antibiotic resistance has   become  one of the top threats to humanity, causing approximately 0.7 million annual deaths across the globe, and the number may exceed to cancer-driven mortality in the near future. Gene mutation and horizontal gene transfer can easily lead to ineffective antibiotic treatment of an infection and enable pathogens  to evolve  the ability   to   evade most   therapeutics. This continuously forces researchers to discover  new antibiotics with improved features, even though antibiotic agents have a weak research pipeline and it takes a long time for most antibiotic drugs to enter the market for practical use. Some researchers take this from a different perspective, including finding alternatives to antibiotics that can treat multidrug-resistant pat...